Pseudomonas aeruginosa PACS2, A0K_RS02170

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PACS2
GCF_000168335.1|latest
Locus Tag
A0K_RS02170
Name
Replicon chromosome
Genomic location 465266 - 466723 (+ strand)

Cross-References

RefSeq ZP_01363331.1
GI 107099413
NCBI Locus Tag A0K_RS02170

Product

Feature Type CDS
Coding Frame 1
Product Name
multidrug transporter
Synonyms
Evidence for Translation
Charge (pH 7) -2.79
Kyte-Doolittle Hydrophobicity Value -0.215
Molecular Weight (kDa) 52.6
Isoelectric Point (pI) 5.32

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
OprM OprM is an outer membrane factor protein found in Pseudomonas aeruginosa and Burkholderia vietnamiensis. It is part of the MexAB-OprM, MexVW-OprM, MexXY-OprM and the AmrAB-OprM complex. ARO:3000379 protein homolog model Perfect 916.8 100.0 3.0.2

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6IOL MEMBRANE PROTEIN 10/30/18 Cryo-EM structure of multidrug efflux pump MexAB-OprM (60 degree state) PSEUDOMONAS AERUGINOSA; PSEUDOMONAS AERUGINOSA PAO1 3.76 ELECTRON MICROSCOPY 100.0
6IOK MEMBRANE PROTEIN 10/30/18 Cryo-EM structure of multidrug efflux pump MexAB-OprM (0 degree state) PSEUDOMONAS AERUGINOSA PAO1 3.64 ELECTRON MICROSCOPY 100.0
3D5K MEMBRANE PROTEIN 05/16/08 Crystal structure of the OprM channel in a non-symmetrical space group PSEUDOMONAS AERUGINOSA 2.4 X-RAY DIFFRACTION 100.0
1WP1 MEMBRANE PROTEIN 08/28/04 Crystal structure of the drug-discharge outer membrane protein, OprM PSEUDOMONAS AERUGINOSA 2.56 X-RAY DIFFRACTION 100.0
4Y1K MEMBRANE PROTEIN 02/07/15 PALMITOYLATED OPRM OUTER MEMBRANE FACTOR PSEUDOMONAS AERUGINOSA 3.8 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000418 (551 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: A0K_RS02170

Human Homologs

References

No references are associated with this feature.