Pseudomonas aeruginosa PACS2, A0K_RS23020

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa PACS2
GCF_000168335.1|latest
Locus Tag
A0K_RS23020
Name
Replicon chromosome
Genomic location 4921782 - 4922924 (+ strand)

Cross-References

RefSeq ZP_01367211.1
GI 107103293
NCBI Locus Tag A0K_RS23020

Product

Feature Type CDS
Coding Frame 1
Product Name
acetoin utilization protein
Synonyms
Evidence for Translation
Charge (pH 7) -6.57
Kyte-Doolittle Hydrophobicity Value -0.127
Molecular Weight (kDa) 41.1
Isoelectric Point (pI) 6.23

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5G10 HYDROLASE 03/23/16 Pseudomonas aeruginosa HDAH bound to 9,9,9 trifluoro-8,8-dihydroy-N-phenylnonanamide PSEUDOMONAS AERUGINOSA 1.71 X-RAY DIFFRACTION 99.2
5G0Y HYDROLASE 03/23/16 Pseudomonas aeruginosa HDAH unliganded. PSEUDOMONAS AERUGINOSA 2.29 X-RAY DIFFRACTION 99.2
5G12 HYDROLASE 03/23/16 Pseudomonas aeruginosa HDAH (Y313F) unliganded. PSEUDOMONAS AERUGINOSA 2.02 X-RAY DIFFRACTION 98.9
5G13 HYDROLASE 03/23/16 Pseudomonas aeruginosa HDAH (H143A) unliganded. PSEUDOMONAS AERUGINOSA 1.99 X-RAY DIFFRACTION 98.9
5G0X HYDROLASE 03/23/16 Pseudomonas aeruginosa HDAH bound to acetate. PSEUDOMONAS AERUGINOSA 1.7 X-RAY DIFFRACTION 99.2
5G11 HYDROLASE 03/23/16 Pseudomonas aeruginosa HDAH bound to PFSAHA. PSEUDOMONAS AERUGINOSA 2.48 X-RAY DIFFRACTION 98.9
5LI3 SIGNALING PROTEIN 07/14/16 Crystal structure of HDAC-like protein from P. aeruginosa in complex with a photo-switchable inhibitor. Pseudomonas aeruginosa 2.4 X-RAY DIFFRACTION 99.2

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001890 (353 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: A0K_RS23020

Human Homologs

Ensembl 110, assembly GRCh38.p14
histone deacetylase 10 [Source:HGNC Symbol;Acc:HGNC:18128]
E-value: 4.8e-39
Percent Identity: 37.0

References

No references are associated with this feature.