Pseudomonas aeruginosa PAO1, PA0179

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0179
Name
Replicon chromosome
Genomic location 204094 - 204459 (- strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248869.1
GI 15595377
Affymetrix PA0179_at
DNASU PaCD00006079
Entrez 879259
GenBank AAG03569.1
INSDC AAG03569.1
NCBI Locus Tag PA0179
protein_id(GenBank) gb|AAG03569.1|AE004455_10|gnl|PseudoCAP|PA0179
TIGR NTL03PA00180
UniParc UPI00000C4F81
UniProtKB Acc Q9I6V3
UniProtKB ID Q9I6V3_PSEAE
UniRef100 UniRef100_W0YKX0
UniRef50 UniRef50_Q8EF67
UniRef90 UniRef90_M4WSE6

Product

Feature Type CDS
Coding Frame 1
Product Name
probable two-component response regulator
Product Name Confidence: Class 3
Synonyms probable chemotaxis response regulator
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.98
Kyte-Doolittle Hydrophobicity Value -0.209
Molecular Weight (kDa) 13.1
Isoelectric Point (pI) 9.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 624 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000177 (373 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0179

Human Homologs

References

Analysis of a chemotaxis operon in Rhizobium meliloti.
Greck M, Platzer J, Sourjik V, Schmitt R
Mol Microbiol 1995 Mar;15(6):989-1000
PubMed ID: 7623670
Tyrosine 106 of CheY plays an important role in chemotaxis signal transduction in Escherichia coli.
Zhu X, Amsler CD, Volz K, Matsumura P
J Bacteriol 1996 Jul;178(14):4208-15
PubMed ID: 8763950