Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA0895
|
Name |
aruC
Synonym: argD Synonym: dapC Synonym: astC |
Replicon | chromosome |
Genomic location | 977910 - 979130 (+ strand) |
Transposon Mutants | 4 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
Comment | aruC is an aminotransferase gene that has dual function in arginine catabolism (as SOAT) and in arginine biosynthesis (as ACOAT) |
RefSeq | NP_249586.1 |
GI | 15596092 |
Affymetrix | PA0895_aruC_at |
Entrez | 878207 |
GenBank | AAG04284.1 |
INSDC | AAG04284.1 |
NCBI Locus Tag | PA0895 |
protein_id(GenBank) | gb|AAG04284.1|AE004524_1|gnl|PseudoCAP|PA0895 |
TIGR | NTL03PA00896 |
UniParc | UPI00001260C7 |
UniProtKB Acc | O30508 |
UniProtKB ID | ARUC_PSEAE |
UniRef100 | UniRef100_O30508 |
UniRef50 | UniRef50_P40732 |
UniRef90 | UniRef90_O30508 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
N2-Succinylornithine 5-aminotransferase (SOAT) = N2-acetylornithine 5-aminotransferase (ACOAT)
|
Synonyms |
N-succinylglutamate 5-semialdehyde dehydrogenase succinylornithine aminotransferase |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
|
Charge (pH 7) | -7.40 |
Kyte-Doolittle Hydrophobicity Value | -0.087 |
Molecular Weight (kDa) | 43.7 |
Isoelectric Point (pI) | 5.80 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 639 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000862 (536 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA0895
Search term: aruC
|
Ensembl
110, assembly
GRCh38.p14
|
ornithine aminotransferase [Source:HGNC Symbol;Acc:HGNC:8091]
E-value:
2.8e-61
Percent Identity:
34.6
|
Cloning and characterization of the aru genes encoding enzymes of the catabolic arginine succinyltransferase pathway in Pseudomonas aeruginosa.
Itoh Y
J Bacteriol 1997 Dec;179(23):7280-90
PubMed ID: 9393691
|
Arginine catabolism and the arginine succinyltransferase pathway in Escherichia coli.
Schneider BL, Kiupakis AK, Reitzer LJ
J Bacteriol 1998 Aug;180(16):4278-86
PubMed ID: 9696779
|
The dual biosynthetic capability of N-acetylornithine aminotransferase in arginine and lysine biosynthesis.
Ledwidge R, Blanchard JS
Biochemistry 1999 Mar 9;38(10):3019-24
PubMed ID: 10074354
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|
N-Succinylated intermediates in an arginine catabolic pathway of Pseudomonas aeruginosa.
Jann A, Stalon V, Wauven CV, Leisinger T, Haas D
Proc Natl Acad Sci U S A 1986 Jul;83(13):4937-41
PubMed ID: 16593724
|