Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1004
|
Name |
nadA
|
Replicon | chromosome |
Genomic location | 1087843 - 1088901 (+ strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | Reaction not utilizing O2 is necessary to produce spermidine in anaerobic conditions, as shown by gap analysis and explained in references. |
RefSeq | NP_249695.1 |
GI | 15596201 |
Affymetrix | PA1004_nadA_at |
Entrez | 883095 |
GenBank | AAG04393.1 |
INSDC | AAG04393.1 |
NCBI Locus Tag | PA1004 |
protein_id(GenBank) | gb|AAG04393.1|AE004533_4|gnl|PseudoCAP|PA1004 |
TIGR | NTL03PA01005 |
UniParc | UPI000012FC67 |
UniProtKB Acc | Q9I4W9 |
UniProtKB ID | NADA_PSEAE |
UniRef100 | UniRef100_Q02IG9 |
UniRef50 | UniRef50_Q8EEN5 |
UniRef90 | UniRef90_Q02IG9 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
quinolinate synthetase A
|
Synonyms |
L-aspartate oxidase (aerobic/anaerobic) NadA |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -9.71 |
Kyte-Doolittle Hydrophobicity Value | -0.037 |
Molecular Weight (kDa) | 38.4 |
Isoelectric Point (pI) | 5.40 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 517 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000967 (536 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1004
Search term: nadA
Search term: quinolinate synthetase A
|
Molecular biology of pyridine nucleotide biosynthesis in Escherichia coli. Cloning and characterization of quinolinate synthesis genes nadA and nadB.
Flachmann R, Kunz N, Seifert J, Gütlich M, Wientjes FJ, Läufer A, Gassen HG
Eur J Biochem 1988 Aug 1;175(2):221-8
PubMed ID: 2841129
|
A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.
Oshima T, Aiba H, Baba T, Fujita K, Hayashi K, Honjo A, Ikemoto K, Inada T, Itoh T, Kajihara M, Kanai K, Kashimoto K, Kimura S, Kitagawa M, Makino K, Masuda S, Miki T, Mizobuchi K, Mori H, Motomura K, Nakamura Y, Nashimoto H, Nishio Y, Saito N, Horiuchi T
DNA Res 1996 Jun 30;3(3):137-55
PubMed ID: 8905232
|
Genetic linkage in Pseudomonas aeruginosa of algT and nadB: mutation in nadB does not affect NAD biosynthesis or alginate production.
DeVries CA, Hassett DJ, Flynn JL, Ohman DE
Gene 1995 Apr 14;156(1):63-7
PubMed ID: 7737518
|