Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1338
|
Name |
ggt
|
Replicon | chromosome |
Genomic location | 1451719 - 1453392 (- strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 3 transposon mutants in orthologs |
RefSeq | NP_250029.1 |
GI | 15596535 |
Affymetrix | PA1338_ggt_at |
Entrez | 882262 |
GenBank | AAG04727.1 |
INSDC | AAG04727.1 |
NCBI Locus Tag | PA1338 |
protein_id(GenBank) | gb|AAG04727.1|AE004563_4|gnl|PseudoCAP|PA1338 |
TIGR | NTL03PA01339 |
UniParc | UPI00000C5321 |
UniProtKB Acc | Q9I406 |
UniProtKB ID | GGT_PSEAE |
UniRef100 | UniRef100_Q9I406 |
UniRef50 | UniRef50_Q9I406 |
UniRef90 | UniRef90_Q9I406 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
gamma-glutamyltranspeptidase precursor
|
Synonyms | |
Evidence for Translation |
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -4.58 |
Kyte-Doolittle Hydrophobicity Value | -0.138 |
Molecular Weight (kDa) | 59.9 |
Isoelectric Point (pI) | 6.21 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
7D9X | TRANSFERASE | 10/14/20 | Highly active mutant W525D of Gamma-glutamyltranspeptidase from Pseudomonas nitroreducens | Pseudomonas nitroreducens | 1.74 | X-RAY DIFFRACTION | 94.8 |
7D9E | TRANSFERASE | 10/13/20 | Gamma-glutamyltranspeptidase from Pseudomonas nitroreducens complexed with L-DON | Pseudomonas nitroreducens | 1.5 | X-RAY DIFFRACTION | 95.4 |
5ZJG | TRANSFERASE | 03/20/18 | Gamma-glutamyltranspeptidase from Pseudomonas nitroreducens complexed with Gly-Gly | Pseudomonas nitroreducens | 1.702 | X-RAY DIFFRACTION | 95.4 |
7D9W | TRANSFERASE | 10/14/20 | Gamma-glutamyltranspeptidase from Pseudomonas nitroreducens complexed with L-DON | Pseudomonas nitroreducens | 1.9 | X-RAY DIFFRACTION | 95.4 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 391 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000352 (854 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1338
Search term: ggt
Search term: gamma-glutamyltranspeptidase precursor
|
Ensembl
110, assembly
GRCh38.p14
|
gamma-glutamyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4250]
E-value:
4.0e-58
Percent Identity:
34.0
|
Ensembl
110, assembly
GRCh38.p14
|
gamma-glutamyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4250]
E-value:
4.0e-58
Percent Identity:
34.0
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Molecular cloning of Escherichia coli K-12 ggt and rapid isolation of gamma-glutamyltranspeptidase.
Suzuki H, Kumagai H, Echigo T, Tochikura T
Biochem Biophys Res Commun 1988 Jan 15;150(1):33-8
PubMed ID: 2892489
|
DNA sequence of the Escherichia coli K-12 gamma-glutamyltranspeptidase gene, ggt.
Suzuki H, Kumagai H, Echigo T, Tochikura T
J Bacteriol 1989 Sep;171(9):5169-72
PubMed ID: 2570061
|
Escherichia coli gamma-glutamyltranspeptidase mutants deficient in processing to subunits.
Hashimoto W, Suzuki H, Nohara S, Kumagai H
Biochem Biophys Res Commun 1992 Nov 30;189(1):173-8
PubMed ID: 1360205
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|