Pseudomonas aeruginosa PAO1, PA1634 (kdpB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1634
Name
kdpB
Synonym: atkB
Replicon chromosome
Genomic location 1777751 - 1779823 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250325.1
GI 15596831
Affymetrix PA1634_kdpB_at
Entrez 883011
GenBank AAG05023.1
INSDC AAG05023.1
NCBI Locus Tag PA1634
protein_id(GenBank) gb|AAG05023.1|AE004591_3|gnl|PseudoCAP|PA1634
TIGR NTL03PA01635
UniParc UPI000012626F
UniProtKB Acc P57698
UniProtKB ID ATKB_PSEAE
UniRef100 UniRef100_P57698
UniRef50 UniRef50_O32328
UniRef90 UniRef90_P57698

Product

Feature Type CDS
Coding Frame 1
Product Name
potassium-transporting ATPase, B chain
Product Name Confidence: Class 2
Synonyms P-type ATPase potassium ion transporter
Evidence for Translation
Charge (pH 7) -0.85
Kyte-Doolittle Hydrophobicity Value 0.339
Molecular Weight (kDa) 73.0
Isoelectric Point (pI) 6.71

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 642 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003740 (509 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1634
Search term: kdpB

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATPase copper transporting beta [Source:HGNC Symbol;Acc:HGNC:870]
E-value: 1.0e-34
Percent Identity: 28.8

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
The phosphorylation site of the Kdp-ATPase of Escherichia coli: site-directed mutagenesis of the aspartic acid residues 300 and 307 of the KdpB subunit.
Puppe W, Siebers A, Altendorf K
Mol Microbiol 1992 Dec;6(23):3511-20
PubMed ID: 1474895