Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1796
|
Name |
folD
|
Replicon | chromosome |
Genomic location | 1946187 - 1947041 (- strand) |
RefSeq | NP_250487.1 |
GI | 15596993 |
Affymetrix | PA1796_folD_at |
DNASU | PaCD00006818 |
Entrez | 880636 |
GenBank | AAG05185.1 |
INSDC | AAG05185.1 |
NCBI Locus Tag | PA1796 |
protein_id(GenBank) | gb|AAG05185.1|AE004605_7|gnl|PseudoCAP|PA1796 |
TIGR | NTL03PA01797 |
UniParc | UPI00000C54A0 |
UniProtKB Acc | Q9I2U6 |
UniProtKB ID | FOLD_PSEAE |
UniRef100 | UniRef100_B7VB83 |
UniRef50 | UniRef50_P51696 |
UniRef90 | UniRef90_A6V726 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
5,10-methylene-tetrahydrofolate dehydrogenase / cyclohydrolase
|
Synonyms | |
Evidence for Translation |
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -5.96 |
Kyte-Doolittle Hydrophobicity Value | 0.053 |
Molecular Weight (kDa) | 30.5 |
Isoelectric Point (pI) | 5.80 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4A5O | OXIDOREDUCTASE | 10/26/11 | Crystal structure of Pseudomonas aeruginosa N5, N10- methylenetetrahydrofolate dehydrogenase-cyclohydrolase (FolD) | PSEUDOMONAS AERUGINOSA PAO1 | 2.2 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 621 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003602 (537 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1796
Search term: folD
|
Ensembl
110, assembly
GRCh38.p14
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434]
E-value:
1.2e-58
Percent Identity:
43.7
|
Ensembl
110, assembly
GRCh38.p14
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like [Source:HGNC Symbol;Acc:HGNC:31865]
E-value:
1.2e-58
Percent Identity:
43.7
|
Ensembl
110, assembly
GRCh38.p14
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434]
E-value:
1.2e-58
Percent Identity:
43.7
|
Ensembl
110, assembly
GRCh38.p14
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like [Source:HGNC Symbol;Acc:HGNC:31865]
E-value:
1.2e-58
Percent Identity:
43.7
|
Purification, characterization, cloning, and amino acid sequence of the bifunctional enzyme 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase from Escherichia coli.
D'Ari L, Rabinowitz JC
J Biol Chem 1991 Dec 15;266(35):23953-8
PubMed ID: 1748668
|
fimA-folD genes linkage in Salmonella identifies a putative junctional site of chromosomal rearrangement in the enterobacterial genome.
Rossolini GM, Muscas P, Chiesurin A, Satta G
FEMS Microbiol Lett 1994 Jun 15;119(3):321-8
PubMed ID: 8050713
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|