Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1845
|
Name |
tsi1
|
Replicon | chromosome |
Genomic location | 2004374 - 2004892 (- strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_250536.1 |
GI | 15597042 |
Affymetrix | PA1845_at |
DNASU | PaCD00006834 |
Entrez | 880643 |
GenBank | AAG05234.1 |
INSDC | AAG05234.1 |
NCBI Locus Tag | PA1845 |
protein_id(GenBank) | gb|AAG05234.1|AE004610_7|gnl|PseudoCAP|PA1845 |
TIGR | NTL03PA01846 |
UniParc | UPI00000C54C9 |
UniProtKB Acc | Q9I2Q0 |
UniProtKB ID | Q9I2Q0_PSEAE |
UniRef100 | UniRef100_W0YR21 |
UniRef50 | UniRef50_A6V6X2 |
UniRef90 | UniRef90_A6V6X2 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Tsi1
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -7.46 |
Kyte-Doolittle Hydrophobicity Value | -0.355 |
Molecular Weight (kDa) | 18.8 |
Isoelectric Point (pI) | 4.61 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4FQB | TOXIN/IMMUNE SYSTEM | 06/25/12 | crystal structure of toxic effector Tse1 in complex with immune protein Tsi1 | Pseudomonas aeruginosa PAO1 | 2.69 | X-RAY DIFFRACTION | 100.0 |
3VPJ | HYDROLASE/HYDROLASE INHIBITOR | 03/04/12 | crystal structure of type VI effector Tse1 from Pseudomonas aeruginosa in complex with immune protein Tsi1 | Pseudomonas aeruginosa | 2.5 | X-RAY DIFFRACTION | 100.0 |
4EQA | UNKNOWN FUNCTION | 04/18/12 | Crystal structure of PA1844 in complex with PA1845 from Pseudomonas aeruginosa PAO1 | Pseudomonas aeruginosa | 1.6 | X-RAY DIFFRACTION | 100.0 |
4FGI | HYDROLASE/HYDROLASE INHIBITOR | 06/04/12 | Structure of the effector - immunity system Tse1 / Tsi1 from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 3.2 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in one genus
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003555 (300 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1845
Search term: tsi1
Search term: Tsi1
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Type VI secretion delivers bacteriolytic effectors to target cells.
Russell AB, Hood RD, Bui NK, LeRoux M, Vollmer W, Mougous JD
Nature 2011 Jul 20;475(7356):343-7
PubMed ID: 21776080
|