Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1898
|
Name |
qscR
Synonym: phzR |
Replicon | chromosome |
Genomic location | 2069490 - 2070203 (+ strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_250589.1 |
GI | 15597095 |
Affymetrix | PA1898_at |
DNASU | PaCD00006854 |
Entrez | 880650 |
GenBank | AAG05287.1 |
INSDC | AAG05287.1 |
NCBI Locus Tag | PA1898 |
protein_id(GenBank) | gb|AAG05287.1|AE004616_1|gnl|PseudoCAP|PA1898 |
TIGR | NTL03PA01899 |
UniParc | UPI00000D4284 |
UniProtKB Acc | G3XD77 |
UniProtKB ID | G3XD77_PSEAE |
UniRef100 | UniRef100_W0YR84 |
UniRef50 | UniRef50_W0YR84 |
UniRef90 | UniRef90_W0YR84 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
quorum-sensing control repressor
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -4.35 |
Kyte-Doolittle Hydrophobicity Value | -0.141 |
Molecular Weight (kDa) | 27.3 |
Isoelectric Point (pI) | 5.91 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
6CBQ | transcription/agonist | 02/05/18 | Crystal structure of QscR bound to agonist S3 | Pseudomonas aeruginosa | 2.8 | X-RAY DIFFRACTION | 100.0 |
6CC0 | TRANSCRIPTION | 02/05/18 | Crystal structure of QscR bound to C12-homoserine lactone | Pseudomonas aeruginosa | 2.5 | X-RAY DIFFRACTION | 100.0 |
3SZT | TRANSCRIPTION | 07/19/11 | Quorum Sensing Control Repressor, QscR, Bound to N-3-oxo-dodecanoyl-L-Homoserine Lactone | Pseudomonas aeruginosa | 2.55 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 174 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001096 (1439 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1898
Search term: qscR
Search term: quorum-sensing control repressor
|
QscR, a modulator of quorum-sensing signal synthesis and virulence in Pseudomonas aeruginosa.
Chugani SA, Whiteley M, Lee KM, D'Argenio D, Manoil C, Greenberg EP
Proc Natl Acad Sci U S A 2001 Feb 27;98(5):2752-7
PubMed ID: 11226312
|
Activity of purified QscR, a Pseudomonas aeruginosa orphan quorum-sensing transcription factor.
Lee JH, Lequette Y, Greenberg EP
Mol Microbiol 2006 Jan;59(2):602-9
PubMed ID: 16390453
|
Phenazine antibiotic biosynthesis in Pseudomonas aureofaciens 30-84 is regulated by PhzR in response to cell density.
Pierson LS 3rd, Keppenne VD, Wood DW
J Bacteriol 1994 Jul;176(13):3966-74
PubMed ID: 8021179
|
Two-component transcriptional regulation of N-acyl-homoserine lactone production in Pseudomonas aureofaciens.
Chancey ST, Wood DW, Pierson LS 3rd
Appl Environ Microbiol 1999 Jun;65(6):2294-9
PubMed ID: 10347004
|