Pseudomonas aeruginosa PAO1, PA1950 (rbsK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1950
Name
rbsK
Replicon chromosome
Genomic location 2135460 - 2136386 (+ strand)

Cross-References

RefSeq NP_250640.1
GI 15597146
Affymetrix PA1950_rbsK_at
DNASU PaCD00006873
Entrez 880829
GenBank AAG05338.1
INSDC AAG05338.1
NCBI Locus Tag PA1950
protein_id(GenBank) gb|AAG05338.1|AE004621_9|gnl|PseudoCAP|PA1950
TIGR NTL03PA01950
UniParc UPI00000C5526
UniProtKB Acc Q9I2F4
UniProtKB ID Q9I2F4_PSEAE
UniRef100 UniRef100_Q9I2F4
UniRef50 UniRef50_E2XV13
UniRef90 UniRef90_A6V6L7

Product

Feature Type CDS
Coding Frame 1
Product Name
ribokinase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -8.67
Kyte-Doolittle Hydrophobicity Value 0.222
Molecular Weight (kDa) 31.8
Isoelectric Point (pI) 4.93

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 564 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003482 (485 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1950
Search term: rbsK
Search term: ribokinase

Human Homologs

Ensembl 110, assembly GRCh38.p14
ribokinase [Source:HGNC Symbol;Acc:HGNC:30325]
E-value: 3.1e-44
Percent Identity: 39.2

References

Molecular cloning and characterization of genes required for ribose transport and utilization in Escherichia coli K-12.
Iida A, Harayama S, Iino T, Hazelbauer GL
J Bacteriol 1984 May;158(2):674-82
PubMed ID: 6327617
Ribokinase from Escherichia coli K12. Nucleotide sequence and overexpression of the rbsK gene and purification of ribokinase.
Hope JN, Bell AW, Hermodson MA, Groarke JM
J Biol Chem 1986 Jun 15;261(17):7663-8
PubMed ID: 3011794
DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication.
Burland V, Plunkett G 3rd, Daniels DL, Blattner FR
Genomics 1993 Jun;16(3):551-61
PubMed ID: 7686882