Pseudomonas aeruginosa PAO1, PA2144 (glgP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2144
Name
glgP
Replicon chromosome
Genomic location 2358364 - 2360802 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250834.1
GI 15597340
Affymetrix PA2144_glgP_at
Entrez 881812
GenBank AAG05532.1
INSDC AAG05532.1
NCBI Locus Tag PA2144
protein_id(GenBank) gb|AAG05532.1|AE004641_11|gnl|PseudoCAP|PA2144
TIGR NTL03PA02144
UniParc UPI00000C55CE
UniProtKB Acc Q9I1X1
UniProtKB ID Q9I1X1_PSEAE
UniRef100 UniRef100_W0YQ89
UniRef50 UniRef50_A9CG13
UniRef90 UniRef90_Q02LT6

Product

Feature Type CDS
Coding Frame 1
Product Name
glycogen phosphorylase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -21.84
Kyte-Doolittle Hydrophobicity Value -0.231
Molecular Weight (kDa) 92.0
Isoelectric Point (pI) 5.64

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 381 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003329 (521 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2144
Search term: glgP

Human Homologs

Ensembl 110, assembly GRCh38.p14
glycogen phosphorylase B [Source:HGNC Symbol;Acc:HGNC:9723]
E-value: 1.4e-216
Percent Identity: 47.6

References

Biosynthesis of bacterial glycogen. Primary structure of Escherichia coli ADP-glucose:alpha-1,4-glucan, 4-glucosyltransferase as deduced from the nucleotide sequence of the glgA gene.
Kumar A, Larsen CE, Preiss J
J Biol Chem 1986 Dec 5;261(34):16256-9
PubMed ID: 3097003
Alpha-glucan phosphorylase from Escherichia coli. Cloning of the gene, and purification and characterization of the protein.
Yu F, Jen Y, Takeuchi E, Inouye M, Nakayama H, Tagaya M, Fukui T
J Biol Chem 1988 Sep 25;263(27):13706-11
PubMed ID: 3047129
Molecular cloning and sequencing of the glycogen phosphorylase gene from Escherichia coli.
Choi YL, Kawamukai M, Utsumi R, Sakai H, Komano T
FEBS Lett 1989 Jan 30;243(2):193-8
PubMed ID: 2645169