Pseudomonas aeruginosa PAO1, PA2374 (tseF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2374
Name
tseF
Replicon chromosome
Genomic location 2626221 - 2626757 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
CommentHcp Secretion Island-III-encoded type VI secretion system (H3-T6SS)

Cross-References

RefSeq NP_251064.1
GI 15597570
Affymetrix PA2374_at
DNASU PaCD00007037
Entrez 877895
GenBank AAG05762.1
INSDC AAG05762.1
NCBI Locus Tag PA2374
protein_id(GenBank) gb|AAG05762.1|AE004663_8|gnl|PseudoCAP|PA2374
TIGR NTL03PA02374
UniParc UPI00000C569A
UniProtKB Acc Q9I1A5
UniProtKB ID Q9I1A5_PSEAE
UniRef100 UniRef100_Q9I1A5
UniRef50 UniRef50_A0A0A1I354
UniRef90 UniRef90_W0YR06

Product

Feature Type CDS
Coding Frame 1
Product Name
TseF
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 1.39
Kyte-Doolittle Hydrophobicity Value -0.700
Molecular Weight (kDa) 19.8
Isoelectric Point (pI) 7.42

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 68 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003152 (329 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2374
Search term: tseF
Search term: TseF

Human Homologs

References

A Pseudomonas T6SS effector recruits PQS-containing outer membrane vesicles for iron acquisition.
Lin J, Zhang W, Cheng J, Yang X, Zhu K, Wang Y, Wei G, Qian PY, Luo ZQ, Shen X
Nat Commun 2017 Mar 28;8:14888
PubMed ID: 28348410