Pseudomonas aeruginosa PAO1, PA2561 (ctpH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2561
Name
ctpH
Replicon chromosome
Genomic location 2894908 - 2896614 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251251.1
GI 15597757
Affymetrix PA2561_at
Entrez 882739
GenBank AAG05949.1
NCBI Locus Tag PA2561
protein_id(GenBank) gb|AAG05949.1|AE004684_4|gnl|PseudoCAP|PA2561
TIGR NTL03PA02561
UniProtKB Acc Q9KWF2
UniProtKB ID Q9KWF2_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
CtpH
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -10.88
Kyte-Doolittle Hydrophobicity Value -0.239
Molecular Weight (kDa) 61.6
Isoelectric Point (pI) 5.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 401 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003009 (461 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2561
Search term: ctpH
Search term: CtpH

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Molecular cloning and characterization of a chemotactic transducer gene in Pseudomonas aeruginosa.
Kuroda A, Kumano T, Taguchi K, Nikata T, Kato J, Ohtake H
J Bacteriol 1995 Dec;177(24):7019-25
PubMed ID: 8522505
Genetic identification of chemotactic transducers for amino acids in Pseudomonas aeruginosa.
Taguchi K, Fukutomi H, Kuroda A, Kato J, Ohtake H
Microbiology (Reading) 1997 Oct;143 ( Pt 10):3223-3229
PubMed ID: 9353923
Identification and characterization of two chemotactic transducers for inorganic phosphate in Pseudomonas aeruginosa.
Wu H, Kato J, Kuroda A, Ikeda T, Takiguchi N, Ohtake H
J Bacteriol 2000 Jun;182(12):3400-4
PubMed ID: 10852870