Pseudomonas aeruginosa PAO1, PA2642 (nuoG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2642
Name
nuoG
Replicon chromosome
Genomic location 2987721 - 2990438 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_251332.1
GI 15597838
Affymetrix PA2642_nuoG_at
Entrez 882349
GenBank AAG06030.1
INSDC AAG06030.1
NCBI Locus Tag PA2642
protein_id(GenBank) gb|AAG06030.1|AE004693_1|gnl|PseudoCAP|PA2642
TIGR NTL03PA02642
UniParc UPI00000C5783
UniProtKB Acc Q9I0J6
UniProtKB ID NUOG_PSEAE
UniRef100 UniRef100_Q9I0J6
UniRef50 UniRef50_P33602
UniRef90 UniRef90_Q9I0J6

Product

Feature Type CDS
Coding Frame 1
Product Name
NADH dehydrogenase I chain G
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (99.00 kDa, PMID:21751344)
Charge (pH 7) -15.20
Kyte-Doolittle Hydrophobicity Value -0.279
Molecular Weight (kDa) 99.0
Isoelectric Point (pI) 5.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Vesicle Class 1
Unknown (This protein may have multiple localization sites) Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 493 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002912 (517 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2642
Search term: nuoG

Human Homologs

Ensembl 110, assembly GRCh38.p14
NADH:ubiquinone oxidoreductase core subunit S1 [Source:HGNC Symbol;Acc:HGNC:7707]
E-value: 3.9e-55
Percent Identity: 26.1
Ensembl 110, assembly GRCh38.p14
NADH:ubiquinone oxidoreductase core subunit S1 [Source:HGNC Symbol;Acc:HGNC:7707]
E-value: 3.9e-55
Percent Identity: 26.1
Ensembl 110, assembly GRCh38.p14
NADH:ubiquinone oxidoreductase core subunit S1 [Source:HGNC Symbol;Acc:HGNC:7707]
E-value: 3.9e-55
Percent Identity: 26.1
Ensembl 110, assembly GRCh38.p14
NADH:ubiquinone oxidoreductase core subunit S1 [Source:HGNC Symbol;Acc:HGNC:7707]
E-value: 3.9e-55
Percent Identity: 26.1
Ensembl 110, assembly GRCh38.p14
NADH:ubiquinone oxidoreductase core subunit S1 [Source:HGNC Symbol;Acc:HGNC:7707]
E-value: 3.9e-55
Percent Identity: 26.1
Ensembl 110, assembly GRCh38.p14
NADH:ubiquinone oxidoreductase core subunit S1 [Source:HGNC Symbol;Acc:HGNC:7707]
E-value: 3.9e-55
Percent Identity: 26.1

References

Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344
The gene locus of the proton-translocating NADH: ubiquinone oxidoreductase in Escherichia coli. Organization of the 14 genes and relationship between the derived proteins and subunits of mitochondrial complex I.
Weidner U, Geier S, Ptock A, Friedrich T, Leif H, Weiss H
J Mol Biol 1993 Sep 5;233(1):109-22
PubMed ID: 7690854