Pseudomonas aeruginosa PAO1, PA2666

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2666
Name
Synonym: ptpS
Replicon chromosome
Genomic location 3015582 - 3015938 (+ strand)

Cross-References

RefSeq NP_251356.1
GI 15597862
Affymetrix PA2666_at
Entrez 882375
GenBank AAG06054.1
INSDC AAG06054.1
NCBI Locus Tag PA2666
protein_id(GenBank) gb|AAG06054.1|AE004695_7|gnl|PseudoCAP|PA2666
TIGR NTL03PA02666
UniParc UPI00000C579A
UniProtKB Acc Q9I0H2
UniProtKB ID Q9I0H2_PSEAE
UniRef100 UniRef100_Q9I0H2
UniRef50 UniRef50_Q9I0H2
UniRef90 UniRef90_Q9I0H2

Product

Feature Type CDS
Coding Frame 1
Product Name
probable 6-pyruvoyl tetrahydrobiopterin synthase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.97
Kyte-Doolittle Hydrophobicity Value -0.545
Molecular Weight (kDa) 13.8
Isoelectric Point (pI) 6.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2OBA LYASE 12/18/06 Pseudomonas aeruginosa 6-pyruvoyl tetrahydrobiopterin synthase Pseudomonas aeruginosa 2.33 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 386 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002891 (526 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2666

Human Homologs

References

No references are associated with this feature.