Pseudomonas aeruginosa PAO1, PA2717 (cpo)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2717
Name
cpo
Replicon chromosome
Genomic location 3072081 - 3072911 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_251407.1
GI 15597913
Affymetrix PA2717_cpo_at
DNASU PaCD00007175
Entrez 882669
GenBank AAG06105.1
INSDC AAG06105.1
NCBI Locus Tag PA2717
protein_id(GenBank) gb|AAG06105.1|AE004700_1|gnl|PseudoCAP|PA2717
TIGR NTL03PA02717
UniParc UPI00000C57C9
UniProtKB Acc Q9I0C5
UniProtKB ID Q9I0C5_PSEAE
UniRef100 UniRef100_Q9I0C5
UniRef50 UniRef50_P22862
UniRef90 UniRef90_Q9I0C5

Product

Feature Type CDS
Coding Frame 1
Product Name
chloroperoxidase precursor
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.12
Kyte-Doolittle Hydrophobicity Value -0.315
Molecular Weight (kDa) 30.4
Isoelectric Point (pI) 5.90

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 346 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002852 (445 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2717
Search term: cpo

Human Homologs

References

Chloroperoxidase-encoding gene from Pseudomonas pyrrocinia: sequence, expression in heterologous hosts, and purification of the enzyme.
Wolfframm C, Lingens F, Mutzel R, van Pée KH
Gene 1993 Aug 16;130(1):131-5
PubMed ID: 8344520
A catalytic triad is required by the non-heme haloperoxidases to perform halogenation.
Pelletier I, Altenbuchner J, Mattes R
Biochim Biophys Acta 1995 Jul 19;1250(2):149-57
PubMed ID: 7632719