Pseudomonas aeruginosa PAO1, PA2801

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2801
Name
Replicon chromosome
Genomic location 3157667 - 3158071 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251491.1
GI 15597997
Affymetrix PA2801_at
DNASU PaCD00007216
Entrez 879843
GenBank AAG06189.1
INSDC AAG06189.1
NCBI Locus Tag PA2801
protein_id(GenBank) gb|AAG06189.1|AE004707_8|gnl|PseudoCAP|PA2801
TIGR NTL03PA02801
UniParc UPI00000C5813
UniProtKB Acc Q9I042
UniProtKB ID Q9I042_PSEAE
UniRef100 UniRef100_Q9I042
UniRef50 UniRef50_Q9I042
UniRef90 UniRef90_Q9I042

Product

Feature Type CDS
Coding Frame 1
Product Name
thiolester hydrolase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -3.88
Kyte-Doolittle Hydrophobicity Value -0.140
Molecular Weight (kDa) 15.0
Isoelectric Point (pI) 6.22

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3QY3 HYDROLASE 03/02/11 PA2801 protein, a putative Thioesterase from Pseudomonas aeruginosa Pseudomonas aeruginosa 1.75 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 223 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002768 (310 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2801

Human Homologs

References

Structure and activity of the Pseudomonas aeruginosa hotdog-fold thioesterases PA5202 and PA2801.
Gonzalez CF, Tchigvintsev A, Brown G, Flick R, Evdokimova E, Xu X, Osipiuk J, Cuff ME, Lynch S, Joachimiak A, Savchenko A, Yakunin AF
Biochem J 2012 Jun 15;444(3):445-55
PubMed ID: 22439787