Pseudomonas aeruginosa PAO1, PA2893 (atuH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2893
Name
atuH
Replicon chromosome
Genomic location 3247369 - 3249195 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251583.1
GI 15598089
Affymetrix PA2893_at
Entrez 882588
GenBank AAG06281.1
INSDC AAG06281.1
NCBI Locus Tag PA2893
protein_id(GenBank) gb|AAG06281.1|AE004715_7|gnl|PseudoCAP|PA2893
TIGR NTL03PA02893
UniParc UPI00000C5868
UniProtKB Acc Q9HZV4
UniProtKB ID Q9HZV4_PSEAE
UniRef100 UniRef100_A0A077JU33
UniRef50 UniRef50_A3YC11
UniRef90 UniRef90_A0A077JU33

Product

Feature Type CDS
Coding Frame 1
Product Name
putative very-long chain acyl-CoA synthetase
Product Name Confidence: Class 4
Synonyms putative short chain dehydrogenase involved in catabolism of citronellol
Evidence for Translation
Charge (pH 7) 5.63
Kyte-Doolittle Hydrophobicity Value -0.224
Molecular Weight (kDa) 67.6
Isoelectric Point (pI) 8.13

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 433 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002680 (421 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2893
Search term: atuH

Human Homologs

Ensembl 110, assembly GRCh38.p14
solute carrier family 27 member 2 [Source:HGNC Symbol;Acc:HGNC:10996]
E-value: 3.3e-98
Percent Identity: 37.4

References

Identification of genes and proteins necessary for catabolism of acyclic terpenes and leucine/isovalerate in Pseudomonas aeruginosa.
Förster-Fromme K, Höschle B, Mack C, Bott M, Armbruster W, Jendrossek D
Appl Environ Microbiol 2006 Jul;72(7):4819-28
PubMed ID: 16820476