Pseudomonas aeruginosa PAO1, PA3030 (mobA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA3030
Name
mobA
Synonym: mobA
Replicon chromosome
Genomic location 3394088 - 3394684 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251720.1
GI 15598226
Affymetrix PA3030_at
Entrez 882980
GenBank AAG06418.1
INSDC AAG06418.1
NCBI Locus Tag PA3030
protein_id(GenBank) gb|AAG06418.1|AE004728_4|gnl|PseudoCAP|PA3030
TIGR NTL03PA03030
UniParc UPI000012F357
UniProtKB Acc O68799
UniProtKB ID MOBA_PSEAE
UniRef100 UniRef100_O68799
UniRef50 UniRef50_O68799
UniRef90 UniRef90_O68799

Product

Feature Type CDS
Coding Frame 1
Product Name
molybdopterin-guanine dinucleotide biosynthesis protein MobA
Product Name Confidence: Class 3
Synonyms probable protein FA
Evidence for Translation
Charge (pH 7) 1.56
Kyte-Doolittle Hydrophobicity Value -0.187
Molecular Weight (kDa) 21.9
Isoelectric Point (pI) 7.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 312 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000557 (1050 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3030
Search term: mobA

Human Homologs

References

The mobA gene is required for assimilatory and respiratory nitrate reduction but not xanthine dehydrogenase activity in Pseudomonas aeruginosa.
Noriega C, Hassett DJ, Rowe JJ
Curr Microbiol 2005 Dec;51(6):419-24
PubMed ID: 16235022
Specific incorporation of molybdopterin in xanthine dehydrogenase of Pseudomonas aeruginosa.
Joshi MS, Rajagopalan KV
Arch. Biochem. Biophys. 1994 Feb;308(2):331-4
PubMed ID: 8109962
Isolation of protein FA, a product of the mob locus required for molybdenum cofactor biosynthesis in Escherichia coli.
Palmer T, Vasishta A, Whitty PW, Boxer DH
Eur. J. Biochem. 1994 Jun;222(2):687-92
PubMed ID: 8020507
The product of the molybdenum cofactor gene mobB of Escherichia coli is a GTP-binding protein.
Eaves DJ, Palmer T, Boxer DH
Eur. J. Biochem. 1997 Jun;246(3):690-7
PubMed ID: 9219527