Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3105
|
Name |
xcpQ
|
Replicon | chromosome |
Genomic location | 3484354 - 3486330 (+ strand) |
Transposon Mutants | 6 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 5 transposon mutants in orthologs |
RefSeq | NP_251795.1 |
GI | 15598301 |
Affymetrix | PA3105_xcpQ_at |
Entrez | 880114 |
GenBank | AAG06493.1 |
INSDC | AAG06493.1 |
NCBI Locus Tag | PA3105 |
protein_id(GenBank) | gb|AAG06493.1|AE004734_11|gnl|PseudoCAP|PA3105 |
TIGR | NTL03PA03105 |
UniParc | UPI000012BC2A |
UniProtKB Acc | P35818 |
UniProtKB ID | GSPD_PSEAE |
UniRef100 | UniRef100_P35818 |
UniRef50 | UniRef50_P35818 |
UniRef90 | UniRef90_P35818 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
general secretion pathway protein D
|
Synonyms | |
Evidence for Translation |
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -5.04 |
Kyte-Doolittle Hydrophobicity Value | -0.123 |
Molecular Weight (kDa) | 70.0 |
Isoelectric Point (pI) | 5.95 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
5MP2 | TRANSPORT PROTEIN | 12/15/16 | XcpQN012 in complex with VHH04 | Lama glama; Pseudomonas aeruginosa | 2.9 | X-RAY DIFFRACTION | 100.0 |
4E9J | PROTEIN TRANSPORT | 03/21/12 | Crystal structure of the N-terminal domain of the secretin XcpQ from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 2.03 | X-RAY DIFFRACTION | 99.2 |
5NGI | TRANSPORT PROTEIN | 03/17/17 | Structure of XcpQN012 | Pseudomonas aeruginosa | 2.98 | X-RAY DIFFRACTION | 100.0 |
4EC5 | PROTEIN TRANSPORT | 03/26/12 | Crystal structure of the S210C (dimer) mutant from the N-terminal domain of the secretin XcpQ from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 2.197 | X-RAY DIFFRACTION | 98.8 |
5WLN | MEMBRANE PROTEIN | 07/27/17 | Cryo-EM structure of the T2SS secretin XcpQ from Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 3.57 | ELECTRON MICROSCOPY | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 348 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000664 (1798 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3105
Search term: xcpQ
Search term: general secretion pathway protein D
|
Xcp-mediated protein secretion in Pseudomonas aeruginosa: identification of two additional genes and evidence for regulation of xcp gene expression.
Akrim M, Bally M, Ball G, Tommassen J, Teerink H, Filloux A, Lazdunski A
Mol Microbiol 1993 Oct;10(2):431-43
PubMed ID: 7934833
|
Formation of oligomeric rings by XcpQ and PilQ, which are involved in protein transport across the outer membrane of Pseudomonas aeruginosa.
Bitter W, Koster M, Latijnhouwers M, de Cock H, Tommassen J
Mol Microbiol 1998 Jan;27(1):209-19
PubMed ID: 9466268
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|