Pseudomonas aeruginosa PAO1, PA3134 (gltX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA3134
Name
gltX
Replicon chromosome
Genomic location 3515416 - 3516900 (- strand)

Cross-References

RefSeq NP_251824.1
GI 15598330
Affymetrix PA3134_gltX_at
Entrez 882647
GenBank AAG06522.1
INSDC AAG06522.1
NCBI Locus Tag PA3134
protein_id(GenBank) gb|AAG06522.1|AE004737_8|gnl|PseudoCAP|PA3134
TIGR NTL03PA03134
UniParc UPI00001363EE
UniProtKB Acc Q9XCL6
UniProtKB ID SYE_PSEAE
UniRef100 UniRef100_Q9XCL6
UniRef50 UniRef50_Q9XCL6
UniRef90 UniRef90_Q9XCL6

Product

Feature Type CDS
Coding Frame 1
Product Name
glutamyl-tRNA synthetase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.58
Kyte-Doolittle Hydrophobicity Value -0.405
Molecular Weight (kDa) 56.7
Isoelectric Point (pI) 6.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5TGT LIGASE 09/28/16 Crystal structure of glytamyl-tRNA synthetase GluRS from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 2.45 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 668 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002464 (552 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3134
Search term: gltX

Human Homologs

Ensembl 97, assembly GRCh38.p12
glutamyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:29419]
E-value: 3.0e-74
Percent Identity: 35.3
Ensembl 97, assembly GRCh38.p12
glutamyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:29419]
E-value: 3.0e-74
Percent Identity: 35.3

References

Cloning and sequencing of the gltX gene, encoding the glutamyl-tRNA synthetase of Rhizobium meliloti A2.
Laberge S, Gagnon Y, Bordeleau LM, Lapointe J
J Bacteriol 1989 Jul;171(7):3926-32
PubMed ID: 2661539