Pseudomonas aeruginosa PAO1, PA3363 (amiR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3363
Name
amiR
Replicon chromosome
Genomic location 3773991 - 3774581 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_252053.1
GI 15598559
Affymetrix PA3363_amiR_at
DNASU PaCD00007474
Entrez 880573
GenBank AAG06751.1
INSDC AAG06751.1
NCBI Locus Tag PA3363
protein_id(GenBank) gb|AAG06751.1|AE004758_8|gnl|PseudoCAP|PA3363
TIGR NTL03PA03363
UniParc UPI0000125985
UniProtKB Acc P10932
UniProtKB ID AMIR_PSEAE
UniRef100 UniRef100_P10932
UniRef50 UniRef50_P10932
UniRef90 UniRef90_P10932

Product

Feature Type CDS
Coding Frame 1
Product Name
aliphatic amidase regulator
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -1.65
Kyte-Doolittle Hydrophobicity Value -0.124
Molecular Weight (kDa) 21.9
Isoelectric Point (pI) 6.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1QO0 BINDING PROTEIN 10/26/99 Amide receptor of the amidase operon of Pseudomonas aeruginosa (AmiC) complexed with the negative regulator AmiR. PSEUDOMONAS AERUGINOSA 2.25 X-RAY DIFFRACTION 98.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 57 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002265 (328 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3363
Search term: amiR

Human Homologs

References

Nucleotide sequence of the aliphatic amidase regulator gene (amiR) of Pseudomonas aeruginosa.
Lowe N, Rice PM, Drew RE
FEBS Lett 1989 Mar 27;246(1-2):39-43
PubMed ID: 2495988
Identification of two new genes in the Pseudomonas aeruginosa amidase operon, encoding an ATPase (AmiB) and a putative integral membrane protein (AmiS).
Wilson SA, Williams RJ, Pearl LH, Drew RE
J Biol Chem 1995 Aug 11;270(32):18818-24
PubMed ID: 7642533