Pseudomonas aeruginosa PAO1, PA3569 (mmsB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3569
Name
mmsB
Replicon chromosome
Genomic location 4001196 - 4002092 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252259.1
GI 15598765
Affymetrix PA3569_mmsB_at
DNASU PaCD00007565
Entrez 879097
GenBank AAG06957.1
NCBI Locus Tag PA3569
protein_id(GenBank) gb|AAG06957.1|AE004778_1|gnl|PseudoCAP|PA3569
TIGR NTL03PA03569
UniProtKB Acc P28811
UniProtKB ID MMSB_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
3-hydroxyisobutyrate dehydrogenase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.68
Kyte-Doolittle Hydrophobicity Value 0.183
Molecular Weight (kDa) 30.5
Isoelectric Point (pI) 6.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 473 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000717 (830 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3569
Search term: mmsB

Human Homologs

Ensembl 110, assembly GRCh38.p14
3-hydroxyisobutyrate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4907]
E-value: 1.6e-61
Percent Identity: 43.1

References

No references are associated with this feature.