Pseudomonas aeruginosa PAO1, PA3584 (glpD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3584
Name
glpD
Replicon chromosome
Genomic location 4016441 - 4017979 (+ strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252274.1
GI 15598780
Affymetrix PA3584_glpD_at
Entrez 880179
GenBank AAG06972.1
INSDC AAG06972.1
NCBI Locus Tag PA3584
protein_id(GenBank) gb|AAG06972.1|AE004779_4|gnl|PseudoCAP|PA3584
TIGR NTL03PA03584
UniParc UPI000012B766
UniProtKB Acc P52111
UniProtKB ID GLPD_PSEAE
UniRef100 UniRef100_P52111
UniRef50 UniRef50_P13035
UniRef90 UniRef90_P52111

Product

Feature Type CDS
Coding Frame 1
Product Name
glycerol-3-phosphate dehydrogenase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 8.39
Kyte-Doolittle Hydrophobicity Value -0.279
Molecular Weight (kDa) 57.1
Isoelectric Point (pI) 8.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 374 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002086 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3584
Search term: glpD

Human Homologs

Ensembl 110, assembly GRCh38.p14
glycerol-3-phosphate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:4456]
E-value: 1.7e-39
Percent Identity: 29.9
Ensembl 110, assembly GRCh38.p14
glycerol-3-phosphate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:4456]
E-value: 1.7e-39
Percent Identity: 29.9
Ensembl 110, assembly GRCh38.p14
glycerol-3-phosphate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:4456]
E-value: 1.7e-39
Percent Identity: 29.9
Ensembl 110, assembly GRCh38.p14
glycerol-3-phosphate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:4456]
E-value: 1.7e-39
Percent Identity: 29.9

References

Cloning and nucleotide sequence of the glpD gene encoding sn-glycerol-3-phosphate dehydrogenase of Pseudomonas aeruginosa.
Schweizer HP, Po C
J Bacteriol 1994 Apr;176(8):2184-93
PubMed ID: 8157588