Pseudomonas aeruginosa PAO1, PA3651 (cdsA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA3651
Name
cdsA
Replicon chromosome
Genomic location 4090091 - 4090906 (- strand)

Cross-References

RefSeq NP_252341.1
GI 15598847
Affymetrix PA3651_cdsA_at
DNASU PaCD00007600
Entrez 880465
GenBank AAG07039.1
INSDC AAG07039.1
NCBI Locus Tag PA3651
protein_id(GenBank) gb|AAG07039.1|AE004785_3|gnl|PseudoCAP|PA3651
TIGR NTL03PA03651
UniParc UPI0000127463
UniProtKB Acc Q59640
UniProtKB ID CDSA_PSEAE
UniRef100 UniRef100_Q59640
UniRef50 UniRef50_Q59640
UniRef90 UniRef90_Q59640

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphatidate cytidylyltransferase
Product Name Confidence: Class 2
Synonyms CDP-diacylglycerol synthase
CDP-diglyceride pyrophosphorylase
Evidence for Translation
Charge (pH 7) 8.46
Kyte-Doolittle Hydrophobicity Value 0.897
Molecular Weight (kDa) 28.9
Isoelectric Point (pI) 10.32

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 587 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002023 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3651
Search term: cdsA

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Molecular cloning and sequencing of the gene for CDP-diglyceride synthetase of Escherichia coli.
Icho T, Sparrow CP, Raetz CR
J Biol Chem 1985 Oct 5;260(22):12078-83
PubMed ID: 2995358
Purification and properties of the membrane-bound CDP-diglyceride synthetase from Escherichia coli.
Sparrow CP, Raetz CR
J Biol Chem 1985 Oct 5;260(22):12084-91
PubMed ID: 2995359
Cloning of the Pseudomonas aeruginosa gene encoding CDP-diglyceride synthetase.
Taguchi K, Fukutomi H, Kuroda A, Kato J, Ohtake H
Gene 1996 Jun;172(1):165-6
PubMed ID: 8654980