Pseudomonas aeruginosa PAO1, PA3687 (ppc)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3687
Name
ppc
Replicon chromosome
Genomic location 4127756 - 4130392 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252377.1
GI 15598883
Affymetrix PA3687_ppc_at
Entrez 879083
GenBank AAG07075.1
INSDC AAG07075.1
NCBI Locus Tag PA3687
protein_id(GenBank) gb|AAG07075.1|AE004788_5|gnl|PseudoCAP|PA3687
TIGR NTL03PA03687
UniParc UPI0000126EFA
UniProtKB Acc Q9HXV3
UniProtKB ID CAPP_PSEAE
UniRef100 UniRef100_Q9HXV3
UniRef50 UniRef50_Q9HXV3
UniRef90 UniRef90_Q9HXV3

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphoenolpyruvate carboxylase
Product Name Confidence: Class 2
Synonyms PEPC
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -9.59
Kyte-Doolittle Hydrophobicity Value -0.205
Molecular Weight (kDa) 97.8
Isoelectric Point (pI) 6.15

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 345 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001990 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3687
Search term: ppc

Human Homologs

References

Catalytic role of an arginine residue in the highly conserved and unique sequence of phosphoenolpyruvate carboxylase.
Yano M, Terada K, Umiji K, Izui K
J Biochem 1995 Jun;117(6):1196-200
PubMed ID: 7490260