Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3769
|
Name |
guaA
|
Replicon | chromosome |
Genomic location | 4225660 - 4227237 (- strand) |
RefSeq | NP_252458.1 |
GI | 15598964 |
Affymetrix | PA3769_guaA_at |
Entrez | 880552 |
GenBank | AAG07156.1 |
INSDC | AAG07156.1 |
NCBI Locus Tag | PA3769 |
protein_id(GenBank) | gb|AAG07156.1|AE004796_1|gnl|PseudoCAP|PA3769 |
TIGR | NTL03PA03769 |
UniParc | UPI000012BD6A |
UniProtKB Acc | Q9HXM6 |
UniProtKB ID | GUAA_PSEAE |
UniRef100 | UniRef100_B7UXJ9 |
UniRef50 | UniRef50_O66601 |
UniRef90 | UniRef90_Q02RS2 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
GMP synthase
|
Synonyms | |
Evidence for Translation |
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -13.83 |
Kyte-Doolittle Hydrophobicity Value | 0.003 |
Molecular Weight (kDa) | 58.0 |
Isoelectric Point (pI) | 5.57 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 652 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001894 (537 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3769
Search term: guaA
Search term: GMP synthase
|
Ensembl
110, assembly
GRCh38.p14
|
guanine monophosphate synthase [Source:HGNC Symbol;Acc:HGNC:4378]
E-value:
2.3e-79
Percent Identity:
35.6
|
Nucleotide sequence of the guaA gene encoding GMP synthetase of Escherichia coli K12.
Tiedeman AA, Smith JM, Zalkin H
J Biol Chem 1985 Jul 25;260(15):8676-9
PubMed ID: 3894345
|
The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families.
Tesmer JJ, Klem TJ, Deras ML, Davisson VJ, Smith JL
Nat Struct Biol 1996 Jan;3(1):74-86
PubMed ID: 8548458
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|