Pseudomonas aeruginosa PAO1, PA3820 (secF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA3820
Name
secF
Replicon chromosome
Genomic location 4276154 - 4277074 (- strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_252509.1
GI 15599015
Affymetrix PA3820_secF_at
Entrez 879904
GenBank AAG07207.1
INSDC AAG07207.1
NCBI Locus Tag PA3820
protein_id(GenBank) gb|AAG07207.1|AE004799_13|gnl|PseudoCAP|PA3820
TIGR NTL03PA03820
UniParc UPI00000C5B27
UniProtKB Acc Q9HXI2
UniProtKB ID SECF_PSEAE
UniRef100 UniRef100_Q9HXI2
UniRef50 UniRef50_E9RGS4
UniRef90 UniRef90_Q9HXI2

Product

Feature Type CDS
Coding Frame 1
Product Name
secretion protein SecF
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -6.76
Kyte-Doolittle Hydrophobicity Value 0.538
Molecular Weight (kDa) 33.0
Isoelectric Point (pI) 4.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 584 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001846 (552 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3820
Search term: secF

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
The secD locus of E.coli codes for two membrane proteins required for protein export.
Gardel C, Johnson K, Jacq A, Beckwith J
EMBO J 1990 Oct;9(10):3209-16
PubMed ID: 2170107
The secD locus of E. coli codes for two membrane proteins required for protein export.
Gardel C, Johnson K, Jacq A, Beckwith J
EMBO J 1990 Dec;9(12):4205-6
PubMed ID: 2249673