Pseudomonas aeruginosa PAO1, PA3896

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3896
Name
Replicon chromosome
Genomic location 4364278 - 4365255 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252585.1
GI 15599091
Affymetrix PA3896_at
DNASU PaCD00007697
Entrez 879660
GenBank AAG07283.1
INSDC AAG07283.1
NCBI Locus Tag PA3896
protein_id(GenBank) gb|AAG07283.1|AE004807_2|gnl|PseudoCAP|PA3896
TIGR NTL03PA03896
UniParc UPI00000C5B64
UniProtKB Acc Q9HXB7
UniProtKB ID Q9HXB7_PSEAE
UniRef100 UniRef100_W0YYW9
UniRef50 UniRef50_G8QCF7
UniRef90 UniRef90_S0IQW3

Product

Feature Type CDS
Coding Frame 1
Product Name
probable 2-hydroxyacid dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 2.39
Kyte-Doolittle Hydrophobicity Value -0.109
Molecular Weight (kDa) 35.6
Isoelectric Point (pI) 8.23

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 641 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001776 (524 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3896

Human Homologs

Ensembl 110, assembly GRCh38.p14
glyoxylate and hydroxypyruvate reductase [Source:HGNC Symbol;Acc:HGNC:4570]
E-value: 1.6e-43
Percent Identity: 44.1

References

No references are associated with this feature.