Pseudomonas aeruginosa PAO1, PA3904

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3904
Name
Replicon chromosome
Genomic location 4373938 - 4374333 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 4 transposon mutants in orthologs
CommentPAAR4, TecT and co-TecT are required for TseT-mediated killing

Cross-References

RefSeq NP_252593.1
GI 15599099
Affymetrix PA3904_i_at
DNASU PaCD00007702
Entrez 878950
GenBank AAG07291.1
INSDC AAG07291.1
NCBI Locus Tag PA3904
protein_id(GenBank) gb|AAG07291.1|AE004808_1|gnl|PseudoCAP|PA3904
TIGR NTL03PA03904
UniParc UPI00000C5B6A
UniProtKB Acc Q9HXA9
UniProtKB ID Q9HXA9_PSEAE
UniRef100 UniRef100_Q9HXA9
UniRef50 UniRef50_Q9HXA9
UniRef90 UniRef90_Q9HXA9

Product

Feature Type CDS
Coding Frame 1
Product Name
PAAR4
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 2.58
Kyte-Doolittle Hydrophobicity Value 0.399
Molecular Weight (kDa) 12.6
Isoelectric Point (pI) 8.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 50 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000092 (1670 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3904
Search term: PAAR4

Human Homologs

References

A type VI secretion system effector delivery mechanism dependent on PAAR and a chaperone-co-chaperone complex.
Burkinshaw BJ, Liang X, Wong M, Le ANH, Lam L, Dong TG
Nat Microbiol 2018 May;3(5):632-640
PubMed ID: 29632369