Pseudomonas aeruginosa PAO1, PA4116 (bphO)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4116
Name
bphO
Replicon chromosome
Genomic location 4604006 - 4604593 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252805.1
GI 15599311
Affymetrix PA4116_at
Entrez 879778
GenBank AAG07503.1
INSDC AAG07503.1
NCBI Locus Tag PA4116
protein_id(GenBank) gb|AAG07503.1|AE004828_4|gnl|PseudoCAP|PA4116
TIGR NTL03PA04116
UniParc UPI00000C5C1B
UniProtKB Acc Q9HWR4
UniProtKB ID Q9HWR4_PSEAE
UniRef100 UniRef100_Q9HWR4
UniRef50 UniRef50_Q9HWR4
UniRef90 UniRef90_Q9HWR4

Product

Feature Type CDS
Coding Frame 1
Product Name
heme oxygenase, BphO
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -4.55
Kyte-Doolittle Hydrophobicity Value -0.279
Molecular Weight (kDa) 21.5
Isoelectric Point (pI) 4.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 33 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001582 (302 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4116
Search term: bphO

Human Homologs

References

The heme oxygenase(s)-phytochrome system of Pseudomonas aeruginosa.
Wegele R, Tasler R, Zeng Y, Rivera M, Frankenberg-Dinkel N
J Biol Chem 2004 Oct 29;279(44):45791-802
PubMed ID: 15310749