Pseudomonas aeruginosa PAO1, PA4117 (bphP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4117
Name
bphP
Replicon chromosome
Genomic location 4604621 - 4606807 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252806.1
GI 15599312
Affymetrix PA4117_at
Entrez 880365
GenBank AAG07504.1
INSDC AAG07504.1
NCBI Locus Tag PA4117
protein_id(GenBank) gb|AAG07504.1|AE004828_5|gnl|PseudoCAP|PA4117
TIGR NTL03PA04117
UniParc UPI0000126A88
UniProtKB Acc Q9HWR3
UniProtKB ID BPHY_PSEAE
UniRef100 UniRef100_Q9HWR3
UniRef50 UniRef50_Q9HWR3
UniRef90 UniRef90_Q9HWR3

Product

Feature Type CDS
Coding Frame 1
Product Name
bacterial phytochrome, BphP
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -15.27
Kyte-Doolittle Hydrophobicity Value -0.200
Molecular Weight (kDa) 80.9
Isoelectric Point (pI) 5.70

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3C2W SIGNALING PROTEIN 01/25/08 Crystal structure of the photosensory core domain of P. aeruginosa bacteriophytochrome PaBphP in the Pfr state Pseudomonas aeruginosa 2.9 X-RAY DIFFRACTION 99.8
3NOU SIGNALING PROTEIN 06/25/10 Light-induced intermediate structure L3 of P. aeruginosa bacteriophytochrome Pseudomonas aeruginosa 3 X-RAY DIFFRACTION 99.8
3IBR TRANSFERASE 07/16/09 Crystal Structure of P. aeruginosa Bacteriophytochrome Photosensory Core Module Mutant Q188L in the Mixed Pr/Pfr State Pseudomonas aeruginosa 2.97 X-RAY DIFFRACTION 99.6
3NOP SIGNALING PROTEIN 06/25/10 Light-induced intermediate structure L1 of Pseudomonas aeruginosa bacteriophytochrome Pseudomonas aeruginosa 2.8 X-RAY DIFFRACTION 99.8
3NHQ SIGNALING PROTEIN 06/14/10 The dark Pfr structure of the photosensory core module of P. aeruginosa Bacteriophytochrome Pseudomonas aeruginosa 2.55 X-RAY DIFFRACTION 99.8
3G6O SIGNALING PROTEIN 02/07/09 Crystal structure of P. aeruginosa bacteriophytochrome PaBphP photosensory core domain mutant Q188L Pseudomonas aeruginosa 2.85 X-RAY DIFFRACTION 99.6
3NOT SIGNALING PROTEIN 06/25/10 Light-induced intermediate structure L2 of P. aeruginosa bacteriophytochrome Pseudomonas Aeruginosa 2.7 X-RAY DIFFRACTION 99.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 615 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001581 (502 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4117
Search term: bphP

Human Homologs

References

Sequence and characterization of a novel chromosomal aminoglycoside phosphotransferase gene, aph (3')-IIb, in Pseudomonas aeruginosa.
Hächler H, Santanam P, Kayser FH
Antimicrob Agents Chemother 1996 May;40(5):1254-6
PubMed ID: 8723476