Pseudomonas aeruginosa PAO1, PA4238 (rpoA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA4238
|
| Name |
rpoA
|
| Replicon | chromosome |
| Genomic location | 4754423 - 4755424 (- strand) |
Cross-References
| RefSeq | NP_252928.1 |
| GI | 15599434 |
| Affymetrix | PA4238_rpoA_at |
| DNASU | PaCD00007837 |
| Entrez | 881813 |
| GenBank | AAG07626.1 |
| INSDC | AAG07626.1 |
| NCBI Locus Tag | PA4238 |
| protein_id(GenBank) | gb|AAG07626.1|AE004841_4|gnl|PseudoCAP|PA4238 |
| TIGR | NTL03PA04239 |
| UniParc | UPI00001346AC |
| UniProtKB Acc | O52760 |
| UniProtKB ID | RPOA_PSEAE |
| UniRef100 | UniRef100_A6UZL3 |
| UniRef50 | UniRef50_Q4K557 |
| UniRef90 | UniRef90_Q4K557 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
DNA-directed RNA polymerase alpha chain
|
| Synonyms | |
| Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (36.65 kDa, PMID:21751344)
|
| Charge (pH 7) | -15.59 |
| Kyte-Doolittle Hydrophobicity Value | -0.249 |
| Molecular Weight (kDa) | 36.6 |
| Isoelectric Point (pI) | 4.62 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 589 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG001472 (553 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA4238
Search term: rpoA
Search term: DNA-directed RNA polymerase alpha chain
|
Human Homologs
References
|
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344
|