Pseudomonas aeruginosa PAO1, PA4330

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4330
Name
Replicon chromosome
Genomic location 4858490 - 4859263 (- strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_253020.1
GI 15599526
Affymetrix PA4330_at
Entrez 881502
GenBank AAG07718.1
INSDC AAG07718.1
NCBI Locus Tag PA4330
protein_id(GenBank) gb|AAG07718.1|AE004849_5|gnl|PseudoCAP|PA4330
TIGR NTL03PA04331
UniParc UPI00000C5CC2
UniProtKB Acc Q9HW71
UniProtKB ID Q9HW71_PSEAE
UniRef100 UniRef100_W1MNL4
UniRef50 UniRef50_Q4K7A4
UniRef90 UniRef90_S0I5N6

Product

Feature Type CDS
Coding Frame 1
Product Name
probable enoyl-CoA hydratase/isomerase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -0.85
Kyte-Doolittle Hydrophobicity Value 0.066
Molecular Weight (kDa) 28.2
Isoelectric Point (pI) 6.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7BOR ISOMERASE 03/19/20 Structure of Pseudomonas aeruginosa CoA-bound OdaA Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.901 X-RAY DIFFRACTION 100.0
7CRD ISOMERASE 08/13/20 Structure of Pseudomonas aeruginosa OdaA Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.901 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 492 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003927 (823 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4330

Human Homologs

Ensembl 110, assembly GRCh38.p14
enoyl-CoA delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:14601]
E-value: 1.1e-29
Percent Identity: 33.1
Ensembl 110, assembly GRCh38.p14
enoyl-CoA delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:14601]
E-value: 1.1e-29
Percent Identity: 33.1
Ensembl 110, assembly GRCh38.p14
enoyl-CoA delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:14601]
E-value: 1.1e-29
Percent Identity: 33.1
Ensembl 110, assembly GRCh38.p14
enoyl-CoA delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:14601]
E-value: 1.1e-29
Percent Identity: 33.1

References

No references are associated with this feature.