Pseudomonas aeruginosa PAO1, PA4443 (cysD)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PAO1 (Stover et al., 2000) GCF_000006765.1|latest
Locus Tag	PA4443
Name	cysD
Replicon	chromosome
Genomic location	4976607 - 4977524 (- strand)
Transposon Mutants	2 transposon mutants in PAO1
Transposon Mutants in orthologs	1 transposon mutants in orthologs

Cross-References

RefSeq	NP_253133.1
GI	15599639
Affymetrix	PA4443_cysD_at
Entrez	880980
GenBank	AAG07831.1
INSDC	AAG07831.1
NCBI Locus Tag	PA4443
protein_id(GenBank)	gb|AAG07831.1|AE004858_9|gnl|PseudoCAP|PA4443
TIGR	NTL03PA04444
UniParc	UPI0000128CD7
UniProtKB Acc	O50273
UniProtKB ID	CYSD_PSEAE
UniRef100	UniRef100_A6VBB6
UniRef50	UniRef50_B0T3J3
UniRef90	UniRef90_A6VBB6

Product

Feature Type	CDS
Coding Frame	1
Product Name	ATP sulfurylase small subunit Product Name Confidence: Class 1
Synonyms	sulfate adenylate transferase subunit 2
Evidence for Translation	Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7)	0.39
Kyte-Doolittle Hydrophobicity Value	-0.551
Molecular Weight (kDa)	35.5
Isoelectric Point (pI)	7.09

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543 Cytoplasmic Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
1ZUN	TRANSFERASE	05/31/05	Crystal Structure of a GTP-Regulated ATP Sulfurylase Heterodimer from Pseudomonas syringae	Pseudomonas syringae; Pseudomonas syringae pv. tomato str. DC3000	2.7	X-RAY DIFFRACTION	94.1

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 369 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004032 (535 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA4443 Search term: cysD Search term: ATP sulfurylase small subunit

Human Homologs

References