Pseudomonas aeruginosa PAO1, PA4759 (dapB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA4759
Name
dapB
Replicon chromosome
Genomic location 5345086 - 5345892 (- strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253447.1
GI 15599953
Affymetrix PA4759_dapB_at
Entrez 881759
GenBank AAG08145.1
INSDC AAB39249.1
NCBI Locus Tag PA4759
protein_id(GenBank) gb|AAG08145.1|AE004889_8|gnl|PseudoCAP|PA4759
TIGR NTL03PA04760
UniParc UPI0000128E8C
UniProtKB Acc P38103
UniProtKB ID DAPB_PSEAE
UniRef100 UniRef100_B7V1H1
UniRef50 UniRef50_Q32K66
UniRef90 UniRef90_B7V1H1

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydrodipicolinate reductase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.64
Kyte-Doolittle Hydrophobicity Value 0.071
Molecular Weight (kDa) 28.3
Isoelectric Point (pI) 5.98

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4YWJ OXIDOREDUCTASE 03/20/15 Crystal structure of 4-hydroxy-tetrahydrodipicolinate reductase (HTPA reductase) from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) 1.8 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 588 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004403 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4759
Search term: dapB

References

Characterization of dapB, a gene required by Pseudomonas syringae pv. tabaci BR2.024 for lysine and tabtoxinine-beta-lactam biosynthesis.
Liu L, Shaw PD
J. Bacteriol. 1997 Jan;179(2):507-13
PubMed ID: 8990304
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994