Pseudomonas aeruginosa PAO1, PA4919 (pncB1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4919
Name
pncB1
Replicon chromosome
Genomic location 5518483 - 5519682 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_253606.1
GI 15600112
Affymetrix PA4919_pncB1_at
Entrez 882212
GenBank AAG08304.1
INSDC AAG08304.1
NCBI Locus Tag PA4919
protein_id(GenBank) gb|AAG08304.1|AE004905_2|gnl|PseudoCAP|PA4919
TIGR NTL03PA04920
UniParc UPI0000131D2F
UniProtKB Acc Q9HUP4
UniProtKB ID PNCB1_PSEAE
UniRef100 UniRef100_Q9HUP4
UniRef50 UniRef50_Q88DF7
UniRef90 UniRef90_Q9HUP4

Product

Feature Type CDS
Coding Frame 1
Product Name
nicotinate phosphoribosyltransferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.52
Kyte-Doolittle Hydrophobicity Value -0.153
Molecular Weight (kDa) 46.1
Isoelectric Point (pI) 6.30

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 184 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003966 (826 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4919
Search term: pncB1

Human Homologs

References

The complete genome sequence of Escherichia coli K-12.
Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y
Science 1997 Sep 5;277(5331):1453-62
PubMed ID: 9278503