Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4951
|
Name |
orn
|
Replicon | chromosome |
Genomic location | 5556281 - 5556823 (- strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 3 transposon mutants in orthologs |
RefSeq | NP_253638.1 |
GI | 15600144 |
Affymetrix | PA4951_orn_at |
Entrez | 878205 |
GenBank | AAG08336.1 |
INSDC | AAG08336.1 |
NCBI Locus Tag | PA4951 |
protein_id(GenBank) | gb|AAG08336.1|AE004908_2|gnl|PseudoCAP|PA4951 |
TIGR | NTL03PA04952 |
UniParc | UPI0000130E89 |
UniProtKB Acc | P57665 |
UniProtKB ID | ORN_PSEAE |
UniRef100 | UniRef100_Q02F67 |
UniRef50 | UniRef50_P45340 |
UniRef90 | UniRef90_Q02F67 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
oligoribonuclease
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -5.38 |
Kyte-Doolittle Hydrophobicity Value | -0.494 |
Molecular Weight (kDa) | 20.8 |
Isoelectric Point (pI) | 5.57 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
7VA2 | HYDROLASE | 08/27/21 | PaOrn Oligoribonuclease D11A mutant with product GMP complex structure | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 2.3 | X-RAY DIFFRACTION | 99.4 |
7V9Z | HYDROLASE | 08/27/21 | PaOrn Oligoribonuclease native structure | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 1.85 | X-RAY DIFFRACTION | 100.0 |
7VA3 | HYDROLASE | 08/27/21 | PaOrn Oligoribonuclease D11A mutant with substrate pGpG complex structure | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT | 1.8 | X-RAY DIFFRACTION | 99.4 |
7VA6 | HYDROLASE | 08/27/21 | PaOrn Oligoribonuclease D11A mutant with RNA GU complex structure | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT | 2.1 | X-RAY DIFFRACTION | 99.4 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 216 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004566 (536 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4951
Search term: orn
Search term: oligoribonuclease
|
Ensembl
110, assembly
GRCh38.p14
|
RNA exonuclease 2 [Source:HGNC Symbol;Acc:HGNC:17851]
E-value:
3.9e-47
Percent Identity:
50.6
|
Oligoribonuclease is encoded by a highly conserved gene in the 3'-5' exonuclease superfamily.
Zhang X, Zhu L, Deutscher MP
J Bacteriol 1998 May;180(10):2779-81
PubMed ID: 9573169
|
Oligoribonuclease is a central feature of cyclic diguanylate signaling in Pseudomonas aeruginosa.
Cohen D, Mechold U, Nevenzal H, Yarmiyhu Y, Randall TE, Bay DC, Rich JD, Parsek MR, Kaever V, Harrison JJ, Banin E
Proc Natl Acad Sci U S A 2015 Sep 8;112(36):11359-64
PubMed ID: 26305928
|