Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA5129
|
Name |
grxC
Synonym: grx |
Replicon | chromosome |
Genomic location | 5777134 - 5777388 (- strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
RefSeq | NP_253816.1 |
GI | 15600322 |
Affymetrix | PA5129_grx_at |
DNASU | PaCD00008207 |
Entrez | 877828 |
GenBank | AAG08514.1 |
INSDC | AAG08514.1 |
NCBI Locus Tag | PA5129 |
protein_id(GenBank) | gb|AAG08514.1|AE004926_4|gnl|PseudoCAP|PA5129 |
TIGR | NTL03PA05130 |
UniParc | UPI000012B7D6 |
UniProtKB Acc | Q9HU55 |
UniProtKB ID | GLRX_PSEAE |
UniRef100 | UniRef100_Q9HU55 |
UniRef50 | UniRef50_P0AC64 |
UniRef90 | UniRef90_Q9HU55 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
GrxC
|
Synonyms |
glutaredoxin |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 0.34 |
Kyte-Doolittle Hydrophobicity Value | -0.087 |
Molecular Weight (kDa) | 9.2 |
Isoelectric Point (pI) | 7.29 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 317 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004722 (536 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA5129
Search term: grxC
Search term: GrxC
|
Two additional glutaredoxins exist in Escherichia coli: glutaredoxin 3 is a hydrogen donor for ribonucleotide reductase in a thioredoxin/glutaredoxin 1 double mutant.
Aslund F, Ehn B, Miranda-Vizuete A, Pueyo C, Holmgren A
Proc Natl Acad Sci U S A 1994 Oct 11;91(21):9813-7
PubMed ID: 7937896
|
Glutaredoxin-3 from Escherichia coli. Amino acid sequence, 1H AND 15N NMR assignments, and structural analysis.
Aslund F, Nordstrand K, Berndt KD, Nikkola M, Bergman T, Ponstingl H, Jörnvall H, Otting G, Holmgren A
J Biol Chem 1996 Mar 22;271(12):6736-45
PubMed ID: 8636094
|
NMR structure of Escherichia coli glutaredoxin 3-glutathione mixed disulfide complex: implications for the enzymatic mechanism.
Nordstrand K, slund F, Holmgren A, Otting G, Berndt KD
J Mol Biol 1999 Feb 19;286(2):541-52
PubMed ID: 9973569
|
Mutation of the gene encoding monothiol glutaredoxin (GrxD) in Pseudomonas aeruginosa increases its susceptibility to polymyxins.
Romsang A, Leesukon P, Duangnkern J, Vattanaviboon P, Mongkolsuk S
Int J Antimicrob Agents 2015 Mar;45(3):314-8
PubMed ID: 25593012
|