Pseudomonas aeruginosa PAO1, PA5143 (hisB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5143
Name
hisB
Replicon chromosome
Genomic location 5791083 - 5791676 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253830.1
GI 15600336
Affymetrix PA5143_hisB_at
DNASU PaCD00008213
Entrez 878789
GenBank AAG08528.1
INSDC AAG08528.1
NCBI Locus Tag PA5143
protein_id(GenBank) gb|AAG08528.1|AE004927_6|gnl|PseudoCAP|PA5143
TIGR NTL03PA05144
UniParc UPI000012C868
UniProtKB Acc Q9HU41
UniProtKB ID HIS7_PSEAE
UniRef100 UniRef100_A6VDR3
UniRef50 UniRef50_Q2VYI7
UniRef90 UniRef90_A5VX72

Product

Feature Type CDS
Coding Frame 1
Product Name
imidazoleglycerol-phosphate dehydratase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.18
Kyte-Doolittle Hydrophobicity Value -0.194
Molecular Weight (kDa) 21.9
Isoelectric Point (pI) 6.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 578 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004736 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5143
Search term: hisB

Human Homologs

References

No references are associated with this feature.