Pseudomonas aeruginosa PAO1, PA5354 (glcE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5354
Name
glcE
Replicon chromosome
Genomic location 6021124 - 6022203 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_254041.1
GI 15600547
Affymetrix PA5354_glcE_at
Entrez 877711
GenBank AAG08739.1
INSDC AAG08739.1
NCBI Locus Tag PA5354
protein_id(GenBank) gb|AAG08739.1|AE004947_9|gnl|PseudoCAP|PA5354
TIGR NTL03PA05355
UniParc UPI00000C5FBD
UniProtKB Acc Q9HTK4
UniProtKB ID Q9HTK4_PSEAE
UniRef100 UniRef100_Q9HTK4
UniRef50 UniRef50_P52073
UniRef90 UniRef90_Q9HTK4

Product

Feature Type CDS
Coding Frame 1
Product Name
glycolate oxidase subunit GlcE
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 3.75
Kyte-Doolittle Hydrophobicity Value -0.047
Molecular Weight (kDa) 38.2
Isoelectric Point (pI) 8.15

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 404 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004920 (479 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5354
Search term: glcE

Human Homologs

References

Cross-induction of glc and ace operons of Escherichia coli attributable to pathway intersection. Characterization of the glc promoter.
Pellicer MT, Fernandez C, Badía J, Aguilar J, Lin EC, Baldom L
J Biol Chem 1999 Jan 15;274(3):1745-52
PubMed ID: 9880556