Pseudomonas aeruginosa PAO1, PA5567

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5567
Name
Synonym: thdF
Replicon chromosome
Genomic location 6260390 - 6261757 (- strand)
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_254254.1
GI 15600760
Affymetrix PA5567_at
Entrez 878126
GenBank AAG08952.1
INSDC AAG08952.1
NCBI Locus Tag PA5567
protein_id(GenBank) gb|AAG08952.1|AE004968_6|gnl|PseudoCAP|PA5567
TIGR NTL03PA05568
UniParc UPI0000137456
UniProtKB Acc Q9HT07
UniProtKB ID MNME_PSEAE
UniRef100 UniRef100_Q9HT07
UniRef50 UniRef50_Q9CLQ1
UniRef90 UniRef90_Q9HT07

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -19.21
Kyte-Doolittle Hydrophobicity Value -0.083
Molecular Weight (kDa) 48.7
Isoelectric Point (pI) 4.93

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 613 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005098 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5567

Human Homologs

Ensembl 110, assembly GRCh38.p14
GTP binding protein 3, mitochondrial [Source:HGNC Symbol;Acc:HGNC:14880]
E-value: 5.7e-63
Percent Identity: 38.5
Ensembl 110, assembly GRCh38.p14
GTP binding protein 3, mitochondrial [Source:HGNC Symbol;Acc:HGNC:14880]
E-value: 5.7e-63
Percent Identity: 38.5

References

Analysis and molecular cloning of genes involved in thiophene and furan oxidation by E. coli.
Alam KY, Worland MJ, Clark DP
Appl Biochem Biotechnol 1990 Spring-Summer;24-25:843-55
PubMed ID: 2162149
Molecular cloning and sequence of the thdF gene, which is involved in thiophene and furan oxidation by Escherichia coli.
Alam KY, Clark DP
J Bacteriol 1991 Oct;173(19):6018-24
PubMed ID: 1917835