Pseudomonas aeruginosa PAO1, PA5568

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5568
Name
Synonym: yidC
Replicon chromosome
Genomic location 6261828 - 6263564 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_254255.1
GI 15600761
Affymetrix PA5568_at
Entrez 878127
GenBank AAG08953.1
INSDC AAG08953.1
NCBI Locus Tag PA5568
protein_id(GenBank) gb|AAG08953.1|AE004968_7|gnl|PseudoCAP|PA5568
TIGR NTL03PA05569
UniParc UPI00000C6077
UniProtKB Acc Q9HT06
UniProtKB ID YIDC_PSEAE
UniRef100 UniRef100_Q9HT06
UniRef50 UniRef50_Q9HT06
UniRef90 UniRef90_Q9HT06

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Detected using LC-MS/MS (64.07 kDa, PMID:21751344)
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 2.81
Kyte-Doolittle Hydrophobicity Value -0.090
Molecular Weight (kDa) 64.1
Isoelectric Point (pI) 7.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Outer Membrane Vesicle Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 584 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005099 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5568

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Physical mapping and nucleotide sequence of the rnpA gene that encodes the protein component of ribonuclease P in Escherichia coli.
Hansen FG, Hansen EB, Atlung T
Gene 1985;38(1-3):85-93
PubMed ID: 2415431
Genes and their organization in the replication origin region of the bacterial chromosome.
Ogasawara N, Yoshikawa H
Mol Microbiol 1992 Mar;6(5):629-34
PubMed ID: 1552862
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344