Pseudomonas aeruginosa UCBPP-PA14, PA14_09270 (pchE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_09270
Name
pchE
Replicon chromosome
Genomic location 785708 - 790024 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 29 transposon mutants in orthologs

Cross-References

RefSeq YP_788893.1
GI 116052263
Entrez 4385700
INSDC ABJ13499.1
NCBI Locus Tag PA14_09270
UniParc UPI00000AFB26
UniProtKB Acc Q02T43
UniProtKB ID Q02T43_PSEAB
UniRef100 UniRef100_Q02T43
UniRef50 UniRef50_Q2T477
UniRef90 UniRef90_A0A080VIX7

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydroaeruginoic acid synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -34.51
Kyte-Doolittle Hydrophobicity Value -0.005
Molecular Weight (kDa) 156.5
Isoelectric Point (pI) 4.97

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7EN2 LIGASE 04/15/21 Pyochelin synthetase, a dimeric nonribosomal peptide synthetase elongation module-after-condensation, condensation Pseudomonas aeruginosa PAO1 3.78 ELECTRON MICROSCOPY 99.0
7EN1 LIGASE 04/15/21 Pyochelin synthetase, a dimeric nonribosomal peptide synthetase elongation module-after-condensation Pseudomonas aeruginosa PAO1 3.47 ELECTRON MICROSCOPY 99.0
7EMY LIGASE 04/15/21 Pyochelin synthetase, a dimeric nonribosomal peptide synthetase elongation module Pseudomonas aeruginosa PAO1 2.97 ELECTRON MICROSCOPY 99.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 551 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001483 (2117 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_09270
Search term: pchE

Human Homologs

Ensembl 110, assembly GRCh38.p14
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 3.5e-13
Percent Identity: 28.6
Ensembl 110, assembly GRCh38.p14
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 3.5e-13
Percent Identity: 28.6
Ensembl 110, assembly GRCh38.p14
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 3.5e-13
Percent Identity: 28.6
Ensembl 110, assembly GRCh38.p14
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 3.5e-13
Percent Identity: 28.6
Ensembl 110, assembly GRCh38.p14
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 3.5e-13
Percent Identity: 28.6

References

No references are associated with this feature.