Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4773
|
Name |
speD2
|
Replicon | chromosome |
Genomic location | 5361586 - 5362068 (+ strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | Required for spermidine synthesis on the bacterial surface. |
Comment | SpeD converts S-adenosylmethionine (SAM) to decarboxylated SAM (dSAM), which is used as a substrate with putrescine to synthesize spermidine by SpeE. |
RefSeq | NP_253461.1 |
GI | 15599967 |
Affymetrix | PA4773_at |
DNASU | PaCD00008070 |
Entrez | 881823 |
GenBank | AAG08159.1 |
INSDC | AAG08159.1 |
NCBI Locus Tag | PA4773 |
protein_id(GenBank) | gb|AAG08159.1|AE004891_1|gnl|PseudoCAP|PA4773 |
TIGR | NTL03PA04774 |
UniParc | UPI0000135DFB |
UniProtKB Acc | Q9HV35 |
UniProtKB ID | SPEH_PSEAE |
UniRef100 | UniRef100_B7V1I5 |
UniRef50 | UniRef50_B7V1I5 |
UniRef90 | UniRef90_B7V1I5 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
SpeD2
|
Synonyms |
hypothetical protein |
Evidence for Translation |
Detected using LC-MS/MS (17.32 kDa, PMID:21751344)
|
Charge (pH 7) | -4.87 |
Kyte-Doolittle Hydrophobicity Value | 0.135 |
Molecular Weight (kDa) | 17.3 |
Isoelectric Point (pI) | 5.17 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 218 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004416 (293 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4773
Search term: speD2
Search term: SpeD2
|
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344
|
Surface-localized spermidine protects the Pseudomonas aeruginosa outer membrane from antibiotic treatment and oxidative stress.
Johnson L, Mulcahy H, Kanevets U, Shi Y, Lewenza S
J Bacteriol 2012 Feb;194(4):813-26
PubMed ID: 22155771
|