Pseudomonas aeruginosa PAO1, PA5107 (blc)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5107
Name
blc
Replicon chromosome
Genomic location 5750961 - 5751530 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253794.1
GI 15600300
Affymetrix PA5107_blc_at
DNASU PaCD00008196
Entrez 880704
GenBank AAG08492.1
INSDC AAG08492.1
NCBI Locus Tag PA5107
protein_id(GenBank) gb|AAG08492.1|AE004923_8|gnl|PseudoCAP|PA5107
TIGR NTL03PA05108
UniParc UPI00000C5F05
UniProtKB Acc Q9HU76
UniProtKB ID Q9HU76_PSEAE
UniRef100 UniRef100_Q9HU76
UniRef50 UniRef50_Q4KJP2
UniRef90 UniRef90_Q9HU76

Product

Feature Type CDS
Coding Frame 1
Product Name
outer membrane lipoprotein Blc
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 0.11
Kyte-Doolittle Hydrophobicity Value -0.433
Molecular Weight (kDa) 21.9
Isoelectric Point (pI) 7.13

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Outer Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 158 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004703 (531 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5107
Search term: blc

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Stationary phase expression of a novel Escherichia coli outer membrane lipoprotein and its relationship with mammalian apolipoprotein D. Implications for the origin of lipocalins.
Bishop RE, Penfold SS, Frost LS, Höltje JV, Weiner JH
J Biol Chem 1995 Sep 29;270(39):23097-103
PubMed ID: 7559452