Pseudomonas aeruginosa PAO1, PA0108 (coIII)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0108
Name
coIII
Replicon chromosome
Genomic location 130680 - 131567 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_248798.1
GI 15595306
Affymetrix PA0108_coIII_at
Entrez 882001
GenBank AAG03498.1
INSDC AAG03498.1
NCBI Locus Tag PA0108
protein_id(GenBank) gb|AAG03498.1|AE004449_7|gnl|PseudoCAP|PA0108
TIGR NTL03PA00109
UniParc UPI00000C4F3D
UniProtKB Acc Q9I724
UniProtKB ID Q9I724_PSEAE
UniRef100 UniRef100_W0YK30
UniRef50 UniRef50_G8PXA6
UniRef90 UniRef90_Q02UX0

Product

Feature Type CDS
Coding Frame 1
Product Name
cytochrome c oxidase, subunit III
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 4.59
Kyte-Doolittle Hydrophobicity Value 0.530
Molecular Weight (kDa) 33.3
Isoelectric Point (pI) 8.73

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 416 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000106 (1040 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0108
Search term: coIII

Human Homologs

Ensembl 86, assembly GRCh38.p7
mitochondrially encoded cytochrome c oxidase III [Source:HGNC Symbol;Acc:HGNC:7422]
E-value: 1.7e-50
Percent Identity: 38.5

References

Cytochrome aa3 of Rhodobacter sphaeroides as a model for mitochondrial cytochrome c oxidase. The coxII/coxIII operon codes for structural and assembly proteins homologous to those in yeast.
Cao J, Hosler J, Shapleigh J, Revzin A, Ferguson-Miller S
J. Biol. Chem. 1992 Dec;267(34):24273-8
PubMed ID: 1332950