Pseudomonas aeruginosa PAO1, PA2382 (lldA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA2382
Name
lldA
Replicon chromosome
Genomic location 2633803 - 2634954 (- strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251072.1
GI 15597578
Affymetrix PA2382_lldA_at
Entrez 880725
GenBank AAG05770.1
INSDC AAG05770.1
NCBI Locus Tag PA2382
protein_id(GenBank) gb|AAG05770.1|AE004664_7|gnl|PseudoCAP|PA2382
TIGR NTL03PA02382
UniParc UPI00000C56A2
UniProtKB Acc Q9I197
UniProtKB ID Q9I197_PSEAE
UniRef100 UniRef100_Q9I197
UniRef50 UniRef50_C9Y9E7
UniRef90 UniRef90_V8E3A5

Product

Feature Type CDS
Coding Frame 1
Product Name
L-lactate dehydrogenase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 5.12
Kyte-Doolittle Hydrophobicity Value -0.134
Molecular Weight (kDa) 42.1
Isoelectric Point (pI) 9.07

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 292 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003145 (334 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2382
Search term: lldA

Human Homologs

Ensembl 86, assembly GRCh38.p7
hydroxyacid oxidase 1 [Source:HGNC Symbol;Acc:HGNC:4809]
E-value: 7.7e-64
Percent Identity: 35.8

References

Cloning of a Neisseria meningitidis gene for L-lactate dehydrogenase (L-LDH): evidence for a second meningococcal L-LDH with different regulation.
Erwin AL, Gotschlich EC
J. Bacteriol. 1996 Aug;178(16):4807-13
PubMed ID: 8759842