Pseudomonas aeruginosa PAO1, PA3182 (pgl)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA3182
Name
pgl
Replicon chromosome
Genomic location 3571621 - 3572337 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251872.1
GI 15598378
Affymetrix PA3182_at
Entrez 882680
GenBank AAG06570.1
INSDC AAG06570.1
NCBI Locus Tag PA3182
protein_id(GenBank) gb|AAG06570.1|AE004742_6|gnl|PseudoCAP|PA3182
TIGR NTL03PA03182
UniParc UPI0000124F8E
UniProtKB Acc Q9X2N2
UniProtKB ID 6PGL_PSEAE
UniRef100 UniRef100_Q9X2N2
UniRef50 UniRef50_Q9X2N2
UniRef90 UniRef90_Q9X2N2

Product

Feature Type CDS
Coding Frame 1
Product Name
6-phosphogluconolactonase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.11
Kyte-Doolittle Hydrophobicity Value 0.044
Molecular Weight (kDa) 25.6
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 292 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002434 (551 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3182
Search term: pgl

Human Homologs

Ensembl 94, assembly GRCh38.p12
6-phosphogluconolactonase [Source:HGNC Symbol;Acc:HGNC:8903]
E-value: 1.5e-15
Percent Identity: 33.8

References

The Pseudomonas aeruginosa devB/SOL homolog, pgl, is a member of the hex regulon and encodes 6-phosphogluconolactonase.
Hager PW, Calfee MW, Phibbs PV
J. Bacteriol. 2000 Jul;182(14):3934-41
PubMed ID: 10869070